A02: Context effects on threat processing in dependence of testosterone levels
The focus will be on the influences of a provocative context on social threat processing in AMD under different testosterone levels.
Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry
A03: Modulation of aggression by acute threat
The neural and neurochemical patterns of acute threat as modulators of aggression in BPD will be investigated in this project.
A04: Implicit chemosensory threat signals as stimulators of amygdala hyperresponsiveness in AMD
We make use of threat-related chemosensory stimuli, namely body odor, acquired during aggressive behavior (boxing) and unconsciously perceived, to investigate heightened amygdala responses to threat stimuli in aggressive patients.
A06: Decoding dynamic reciprocal neural mechanism underlying reactive aggression: Insights from fMRI and fNIRS hyperscanning
The project employs fMRI and functional near-infrared spectroscopy (fNIRS) hyperscanning techniques to explore how brain-to-brain synchrony and dynamic processes within peer dyads facilitate or inhibit aggressive behavior under diverse levels of provocation in adolescent patients and controls.
A08: The metabolic lung-brain axis in aggressive behavior in patients with AMD
Beta-hydroxy-butyrate (BHB), a ketone body, is negatively associated with aggressive behavior.
B01: Neurobehavioral effects of repetitive prefrontal transcranial direct current stimulation (tDCS) on pathological aggression
TDCS will be used as an interventional tool to decrease aggression.
B02: Young offenders’ self-regulation deficit as a common mechanism for aggressive behavior and psychopathology - neural mechanisms and role of adverse childhood experiences
This project aims to identify cognitive and emotion control deficits in the context of negative valence and threat interference and their association with ACE in young offenders.
B04: Investigating psychological and neural correlates of intimate partner violence
Focus on the neural correlates of characterizing cognitive control deficits during conflict situations.
B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts
Focus on the investigation of a lack of cognitive control in bullies and victims that contributes to the risk of developing mental health problems.
C03: Distributed network control and interventions to frustrative non-reward and threat triggered aggressions
Investigate context-dependent aggression triggered by frustrative non-reward or acute social threats.
C04: The sex-specific role of genes, early adversity, peers, community violence, and puberty related endocrinological changes in adolescent pathological aggression
Address sex-specific NVS (reactive aggression) and CS (different dimensions of psychopathy, proactive aggression) associated risk factors, and risk factor-based biosignatures.
C06: Brain mechanisms differentiating aggressive vs. non-aggressive psychopathology as sequelae of early life maltreatment
Identify specific neuronal mechanisms related to the NVS and CS in female and male clinical samples with a history of early-life maltreatment (ELM) who exhibit externalizing, aggressive psychopathologies as opposed to internalizing, non-aggressive psychopathologies.
Q01: Recruitment and biotyping transdiagnostic risk mechanisms for aggressive behaviors in mental disorders across the life span
Tobias Banaschewski
Thomas Frodl
Sabine Herpertz
Andreas Reif
Christine Margarete Freitag
Ute Habel
Kerstin Konrad
Service project
RWTH Aachen
Central Institute of Mental Health
Heidelberg University
Goethe University Frankfurt
Biological Psychiatry
Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry
The central recruitment platform for collecting and curating a longitudinal dataset for studying individual aggression dynamics related to the neural, cognitive-emotional, neurobiological, psychopathological and environmental factors in patient groups.