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NEUROPSYCHOBIOLOGY
OF AGGRESSION

A Transdiagnostic Approach
in Mental Disorders

RDoC Domains

This Transregional Collaborative Research Center 379 (TRR) will follow the Research Domain Criteria (RDoC) framework, investigating aggression in a transdiagnostic manner. Within the RDoC's "negative valence system" (NVS) and "cognitive system" (CS) the TRR aims to identify and characterize specific biosignatures and predict aggressive behavior.

Multidimensional scale

The TRR will seek to identify and define these mechanisms on a multilevel scale, advancing a detailed understanding of the biology, psychology, and physiology of specific aggressive biosignatures across mental disorders.

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From Early Adolescence until Adulthood

Finally, the TRR aims to address the temporal stability of AMD and the (dys-)functional NVS and CS during development from early adolescence until adulthood and during the disease course.

Area A Projects on
Negative Valence
Area B Projects on
Cognitive Control
Area C Projects on the
Interaction of A & C
Z: Central Service Central Service Projects