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Collaborative Research Center / Transregio 379: Neuropsychobiology of Aggression

A Transdiagnostic Approach in Mental Disorders

RWTH Aachen – Heidelberg University – Frankfurt University

Spokesperson: Ute Habel

Line art drawing of a lab situation with computer charts, books, microscope, and various utilities

How does aggressive behavior arise in patients with mental disorders? What role do cognitive, environmental, and biological factors, as well as disease symptoms, play in understanding and the occurrence of aggressive behavior? How can we treat aggressive behavior in patients with mental disorders better? A team of researchers from various universities is addressing these questions through a longitudinal, developmental, multidimensional, transdiagnostic approach in the TRR 379. They aim at identifying transdiagnostic biosignatures to enable a more specific prevention and treatment.

Recent

What is B02 about

B02: Young offenders’ self-regulation deficit as a common mechanism for aggressive behavior and psychopathology - neural mechanisms and role of adverse childhood experiences

We would love to take you on a journey through our project. Please find here a video explaining a bit about the subproject “B02: Young offenders’ self-regulation deficit as a common mechanism for aggressive behavior and psychopathology - neural mechanisms and role of adverse childhood experiences”

2nd TRR 379 Retreat: Building Momentum for the Future

The 2nd TRR 379 Retreat brought together nearly 100 team members on February 12-13, 2026, for two days of productive scientific exchange and collaboration. Following the successful first retreat in 2025, this year’s event strengthened connections across all project areas and generated excitement for the work ahead.

2nd TRR 379 Retreat – February 12th & 13th, 2026

The 2nd TRR 379 Retreat will take place on Thursday, 12th, and Friday, 13th February 2026, bringing together all members of the TRR 379 community for two days of scientific exchange, discussion, and networking. The retreat provides a comprehensive program designed to showcase the latest research progress, foster collaboration across project areas, and reflect on the past year of the TRR.

Results of the DFG Team Statistics 2025

Following the conclusion of the 2025 reporting year, we have analyzed the data from our coordinated programs. Transparency is a key component of our research culture, which is why we are sharing a detailed look at the people behind TRR 379.