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B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts

Focus on the investigation of a lack of cognitive control in bullies and victims that contributes to the risk of developing mental health problems. Therefore, the project will assess bullies and their victims in real-life and digital social interactions to investigate how aberrant cognitive and affective prefrontal control and sensitivity to peer rejection with accompanied alterations in autonomic arousal may increase externalizing and internalizing behavior. To this end, a unique combination of ambulatory assessments of (cyber-)bullying, functional neuroimaging (emotion regulation, inhibition, social exclusion), physiological assessments (heart rate variability) and clinical trait-related questionnaires will be applied. Decoding dynamic

Contributors

Tobias Banaschewski

B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts Q01: Recruitment and biotyping transdiagnostic risk mechanisms for aggressive behaviors in mental disorders across the life span Q03: Integrated Research Training Group (RTG) Principal investigator Research training group (RTG) committee member Central Institute of Mental Health Heidelberg University

Medical Director of the Clinic for Child and Adolescent Psychiatry and Psychotherapy and Deputy Director of the Central Institute of Mental Health.

Nathalie Holz

B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts Principal investigator Central Institute of Mental Health Heidelberg University

Nathalie Holz is leader of the research group Developmental neuroscience in psychiatry at the ZI Mannheim.

Publications

Parsing Autism Heterogeneity: Transcriptomic Subgrouping of Imaging-Derived Phenotypes in Autism

Tobias Banaschewski Andreas G Chiocchetti Christine Ecker B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts C05: The neuroanatomical underpinnings of clinical aggression and their relationship with the negative valence and cognitive control systems C04: The sex-specific role of genes, early adversity, peers, community violence, and puberty related endocrinological changes in adolescent pathological aggression

Neurodevelopmental conditions, such as autism, are highly heterogeneous at both the mechanistic and phenotypic levels. Therefore, parsing heterogeneity is vital for uncovering underlying processes that could inform the development of targeted, personalized support.

The long-term correlates of developmental stress on whole-brain functional connectivity during emotion regulation

Tobias Banaschewski Nathalie Holz Q01: Recruitment and biotyping transdiagnostic risk mechanisms for aggressive behaviors in mental disorders across the life span B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts Interaction of negative valence system and cognitive system

Early life stress is associated with alterations in brain function and connectivity during affective processing, especially in the fronto-limbic pathway. However, most of the previous studies were limited to a small set of priori-selected regions and did not address the impact of stress timing on functional connectivity.