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Julius-Maximilians University Würzburg

Julius-Maximilians University Würzburg is a prestigious public research university founded in 1402. It is renowned for its contributions to natural sciences, medicine, and humanities, and has produced several Nobel laureates. The university fosters a vibrant academic community and emphasizes interdisciplinary research and global collaboration.

Contributors

Projects

A02: Context effects on threat processing in dependence of testosterone levels

Isabel Neumann Katja Bertsch Nick Worm Sabine Herpertz Ute Habel RWTH Aachen Heidelberg University Julius-Maximilians University Würzburg Biological Psychiatry Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry Negative valence system

The focus will be on the influences of a provocative context on social threat processing in AMD under different testosterone levels. Specifically, the project aims to analyze the modulating function of context under testosterone application versus suppression on threat sensitivity in healthy controls as well as patient groups. Additionally, we will determine the influence of endogenous hormone variations (testosterone, oxytocin, estrogen and cortisol) on NVS in high versus low aggressive patients in a large group of patients recruited in Q01. With this sample, we will try to identify multidimensional biosignatures based on hormonal levels in combination with fMRI measures of amygdala and amygdala-prefrontal connectivity, NVS measures by questionnaires, aggression measures and psychopathological data.

B04: Investigating psychological and neural correlates of intimate partner violence

Andreas Meyer-Lindenberg Julia Schräder Katja Bertsch Linda Wilkin-Krug Lisa Wagels RWTH Aachen Central Institute of Mental Health Julius-Maximilians University Würzburg Biological Psychiatry Cognitive system Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

Focus on the neural correlates of characterizing cognitive control deficits during conflict situations. The project will investigate patients with varying levels of cognitive control along with their close partners (sibling or intimate partner) to identify the dynamics of self-regulation and co-regulation in provoked conflict situations in patients with control deficits. To identify the precursors and dynamics of conflict escalation, the project will apply measures of behavioral reactions, skin conductance, simulated or real conflict, fMRI and fMRI-hyperscanning techniques and physiological measures. Neuroimaging data will also be combined with information on stress, control and conflicts in real-life via EMA.