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Central Institute of Mental Health

The Central Institute of Mental Health (Zentralinstitut für Seelische Gesundheit) in Mannheim, Germany, is a leading psychiatric research institution affiliated with Heidelberg University. It specializes in research, treatment, and education related to mental health disorders, neuroscience, and psychosocial factors influencing mental well-being. The institute plays a crucial role in advancing psychiatric knowledge and developing innovative therapies through interdisciplinary collaboration and state-of-the-art facilities.

Tobias Banaschewski

B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts Q01: Recruitment and biotyping transdiagnostic risk mechanisms for aggressive behaviors in mental disorders across the life span Q03: Integrated Research Training Group (RTG) Principal investigator Central Institute of Mental Health Heidelberg University

Gabriele Ende

A03: Modulation of aggression by acute threat A08: The metabolic lung-brain axis in aggressive behavior in patients with AMD Q02: Data management for computational modelling Principal investigator Heidelberg University Central Institute of Mental Health

Gabriele Ende is a researcher associated with the Central Institute of Mental Health (ZI) in Mannheim, Germany.

Nathalie Holz

B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts Principal investigator Central Institute of Mental Health Heidelberg University

Andreas Meyer-Lindenberg

A05: Peripersonal space violations and social threat: daily-life psychological and neural mechanisms of environmental risk for reactive aggression A06: Decoding dynamic reciprocal neural mechanism underlying reactive aggression: Insights from fMRI and fNIRS hyperscanning B04: Investigating psychological and neural correlates of intimate partner violence Principal investigator Central Institute of Mental Health Heidelberg University

Andreas Meyer-Lindenberg is a distinguished psychiatrist and neuroscientist based in Germany, renowned for his groundbreaking research on the neurobiological underpinnings of psychiatric disorders.

Christian Paret

B03: A process-based brain-computer interface to modulate aggressive behavior – a real-time fMRI neurofeedback study Principal investigator Central Institute of Mental Health Heidelberg University

Christian Schmahl

A03: Modulation of aggression by acute threat Principal investigator Central Institute of Mental Health Heidelberg University

Heike Tost

A05: Peripersonal space violations and social threat: daily-life psychological and neural mechanisms of environmental risk for reactive aggression Principal investigator Central Institute of Mental Health Heidelberg University

Wolfgang Weber-Fahr

C03: Distributed network control and interventions to frustrative non-reward and threat triggered aggressions Principal investigator Central Institute of Mental Health Heidelberg University

A03: Modulation of aggression by acute threat

Gabriele Ende Christian Schmahl Central Institute of Mental Health Negative valence system Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

The neural and neurochemical patterns of acute threat as modulators of aggression in BPD will be investigated in this project.

A05: Peripersonal space violations and social threat: daily-life psychological and neural mechanisms of environmental risk for reactive aggression

Heike Tost Andreas Meyer-Lindenberg Central Institute of Mental Health Negative valence system Human Cognitive and Systems Neuroscience Biological Psychiatry

Peripersonal space, the representation of the space immediately surrounding the body, will be studied as an underlying factor for threat experience.

A06: Decoding dynamic reciprocal neural mechanism underlying reactive aggression: Insights from fMRI and fNIRS hyperscanning

Kerstin Konrad Andreas Meyer-Lindenberg Vanessa Reindl RWTH Aachen Central Institute of Mental Health Negative valence system Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

The project employs fMRI and functional near-infrared spectroscopy (fNIRS) hyperscanning techniques to explore how brain-to-brain synchrony and dynamic processes within peer dyads facilitate or inhibit aggressive behavior under diverse levels of provocation in adolescent patients and controls.

A08: The metabolic lung-brain axis in aggressive behavior in patients with AMD

Thomas Frodl David Slattery Gabriele Ende RWTH Aachen Goethe University Frankfurt Central Institute of Mental Health Negative valence system Biological Psychiatry Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

Beta-hydroxy-butyrate (BHB), a ketone body, is negatively associated with aggressive behavior.

B03: A process-based brain-computer interface to modulate aggressive behavior – a real-time fMRI neurofeedback study

Klaus Mathiak Christian Paret Jana Zweerings RWTH Aachen Central Institute of Mental Health Cognitive system Biological Psychiatry

Probe the self-regulation of CS networks in adults and adolescents diagnosed with mental disorders related to frequent stress-associated affective outbursts and aggressive symptoms in posttraumatic stress disorder (PTSD), and BPD.

B04: Investigating psychological and neural correlates of intimate partner violence

Lisa Wagels Andreas Meyer-Lindenberg Katja Bertsch RWTH Aachen Central Institute of Mental Health Julius-Maximilians University Würzburg Cognitive system Biological Psychiatry Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

Focus on the neural correlates of characterizing cognitive control deficits during conflict situations.

B05: Predictors and (neuro-)biological correlates of (cyber-)bullying and victimization in real-life contexts

Nathalie Holz Tobias Banaschewski Central Institute of Mental Health Cognitive system Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

Focus on the investigation of a lack of cognitive control in bullies and victims that contributes to the risk of developing mental health problems.

C03: Distributed network control and interventions to frustrative non-reward and threat triggered aggressions

Wolfgang Kelsch Wolfgang Weber-Fahr Johannes Gutenberg University Mainz Central Institute of Mental Health Interaction of negative valence system and cognitive system Biological Psychiatry Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

Investigate context-dependent aggression triggered by frustrative non-reward or acute social threats.

Q01: Recruitment and biotyping transdiagnostic risk mechanisms for aggressive behaviors in mental disorders across the life span

Tobias Banaschewski Thomas Frodl Sabine Herpertz Andreas Reif Christine Margarete Freitag Ute Habel Kerstin Konrad Service project RWTH Aachen Central Institute of Mental Health Heidelberg University Goethe University Frankfurt Biological Psychiatry Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry

The central recruitment platform for collecting and curating a longitudinal dataset for studying individual aggression dynamics related to the neural, cognitive-emotional, neurobiological, psychopathological and environmental factors in patient groups.

Q02: Data management for computational modelling

Michael Hanke Gabriele Ende Christine Ecker Klaus Mathiak Service project Research Center Jülich (FZJ) Central Institute of Mental Health Goethe University Frankfurt RWTH Aachen

Data management and training platform.

Q03: Integrated Research Training Group (RTG)

David Slattery Lisa Wagels Tobias Banaschewski Service project Goethe University Frankfurt RWTH Aachen Central Institute of Mental Health

Bundle all training and mentoring activities in a research training group (RTG) for the young researchers participating in this collaborative research center.

Related to this project site #