Wiebke Hennig

Link questionnaire measures of aggression to specific neural substrates using structural MRI. The resulting patterns of aggression-related neuroanatomical variability will be co- registered with the Allen Human Brain Atlas providing gene-expression data, to highlight genes with a spatial pattern of expression that matches the neuroimaging findings. Utilizing the neurotypical control data, a normative model of neuroanatomical diversity within the NVS and CS will be established to quantify neuroanatomical abnormalities within these systems in individual cases.

Data management and training platform. A decentralized data management infrastructure will help focus on developmental and therapeutic longitudinal data, training all participating researchers in the necessary skills for future use. This strategy will lay the foundations for further data-driven computational modelling projects in the next funding period. This is a distributed project, with representatives at all main TRR379 sites. As a key software solution, this project employs DataLad. DataLad is a data management software designed to facilitate the organization, sharing, and reproducibility of scientific datasets. It integrates version control with data handling, allowing researchers to track changes, collaborate efficiently, and ensure the accessibility and integrity of their data. By leveraging tools like Git and Git- annex, DataLad provides a streamlined way to manage large datasets, making it particularly valuable in fields like neuroimaging and bioinformatics.